首页 | 本学科首页   官方微博 | 高级检索  
     


Precise nanomedicine for intelligent therapy of cancer
Authors:Huabing Chen  Zhanjun Gu  Hongwei An  Chunying Chen  Jie Chen  Ran Cui  Siqin Chen  Weihai Chen  Xuesi Chen  Xiaoyuan Chen  Zhuo Chen  Baoquan Ding  Qian Dong  Qin Fan  Ting Fu  Dayong Hou  Qiao Jiang  Hengte Ke  Xiqun Jiang  Gang Liu  Suping Li  Tianyu Li  Zhuang Liu  Guangjun Nie  Muhammad Ovais  Daiwen Pang  Nasha Qiu  Youqing Shen  Huayu Tian  Chao Wang  Hao Wang  Ziqi Wang  Huaping Xu  Jiang-Fei Xu  Xiangliang Yang  Shuang Zhu  Xianchuang Zheng  Xianzheng Zhang  Yanbing Zhao  Weihong Tan  Xi Zhang  Yuliang Zhao
Affiliation:1.State Key Laboratory of Radiation Medicine and Protection, Jiangsu Key Laboratory of Neuropsychiatric Diseases, College of Pharmaceutical Sciences,Soochow University,Suzhou,China;2.Institute of High Energy Physics,Chinese Academy of Sciences,Beijing,China;3.CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology of China,Beijing,China;4.University of Chinese Academy of Sciences,Beijing,China;5.Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun,China;6.University of Science and Technology of China,Hefei,China;7.Jilin Biomedical Polymers Engineering Laboratory,Changchun,China;8.Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, State Key Laboratory of Virology, and Institute for Advanced Studies,Wuhan University,Wuhan,China;9.Center for Bionanoengineering and Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering,Zhejiang University,Hangzhou,China;10.Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry,Wuhan University,Wuhan,China;11.Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering,National Institutes of Health,Bethesda,USA;12.Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province,Hunan University,Changsha,China;13.Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials,Soochow University,Suzhou,China;14.Department of Polymer Science and Engineering, College of Chemistry and Chemical Engineering,Nanjing University,Nanjing,China;15.State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health,Xiamen University,Xiamen,China;16.Department of Chemistry,Tsinghua University,Beijing,China;17.National Engineering Research Center for Nanomedicine, College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan,China;18.Department of Chemistry and Department of Physiology and Functional Genomics, Center for Research at Bio/nano Interface, Health Cancer Center, UF Genetics Institute and McKnight Brain Institute,University of Florida,Gainesville,USA
Abstract:Precise nanomedicine has been extensively explored for efficient cancer imaging and targeted cancer therapy, as evidenced by a few breakthroughs in their preclinical and clinical explorations. Here, we demonstrate the recent advances of intelligent cancer nanomedicine, and discuss the comprehensive understanding of their structure-function relationship for smart and efficient cancer nanomedicine including various imaging and therapeutic applications, as well as nanotoxicity. In particular, a few emerging strategies that have advanced cancer nanomedicine are also highlighted as the emerging focus such as tumor imprisonment, supramolecular chemotherapy, and DNA nanorobot. The challenge and outlook of some scientific and engineering issues are also discussed in future development. We wish to highlight these new progress of precise nanomedicine with the ultimate goal to inspire more successful explorations of intelligent nanoparticles for future clinical translations.
Keywords:
本文献已被 CNKI SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号