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DNA Cleavage of the Copper(II) Complexes with a Polyamine Ditopic Ligand
作者姓名:Yi Bin WEI  Pin YANG* Institute of Molecular Science  Chemical Biology and Molecular Engineering Laboratory of Education Ministry  Shanxi University  Taiyuan
作者单位:Yi Bin WEI,Pin YANG* Institute of Molecular Science,Chemical Biology and Molecular Engineering Laboratory of Education Ministry,Shanxi University,Taiyuan 030006
摘    要:The investigations on simple and efficient reagents, which can cleave nucleic acids undermild conditions have been attracted considerable attentions1,2. Generally, in order toeliminate the possibility of significant cytotoxic side effect of reactive oxygen species,pathways that result in DNA cleavage by hydrolysis mechanisms are preferable3,4. Wehave reported two novel metal complexes magnesium (II)-diethylenetriamine (dien) andcopper (II)-L-histidine systems that both can effectively promo…

关 键 词:铜化合物  聚胺  DNA  向心配合体

DNA Cleavage of the Copper(II) Complexes with a Polyamine Ditopic Ligand
Yi Bin WEI,Pin YANG* Institute of Molecular Science,Chemical Biology and Molecular Engineering Laboratory of Education Ministry,Shanxi University,Taiyuan .DNA Cleavage of the Copper(II) Complexes with a Polyamine Ditopic Ligand[J].Chinese Chemical Letters,2005,16(4):537-540.
Authors:Yi Bin WEI  Pin YANG Institute of Molecular Science  Chemical Biology and Molecular Engineering Laboratory of Education Ministry  Shanxi University  Taiyuan
Institution:Yi Bin WEI,Pin YANG* Institute of Molecular Science,Chemical Biology and Molecular Engineering Laboratory of Education Ministry,Shanxi University,Taiyuan 030006
Abstract:
Keywords:Hydrolytic cleavage  copper complex  binuclear  
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