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Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity
Authors:Fang Zhiyuan  Huang Jing  Lie Puchang  Xiao Zhuo  Ouyang Chuanyan  Wu Qing  Wu Yixing  Liu Guodong  Zeng Lingwen
Institution:South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510663, China.
Abstract:A lateral flow nucleic acid biosensor based on copper-dependent DNA-cleaving DNAzyme and gold nanoparticles has been developed for the visual detection of copper ions (Cu(2+)) in an aqueous solution with a detection limit of 10 nM.
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