Synthesis of 1-alkyl-4-imidazolecarboxylates: a catch and release strategy |
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Authors: | De Luca Lidia Giacomelli Giampaolo Porcheddu Andrea |
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Affiliation: | Dipartimento di Chimica, Università degli Studi di Sassari, Via Vienna 2, I-07100 Sassari, Italy. |
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Abstract: | The novel alkyl N-methyl-N-polystyreneamino-2-isocyanoacrylate was used for the synthesis of 1-substituted imidazole-4-carboxylates utilizing a "catch and release" methodology. The reactions were performed under microwave irradiation, affording the title compounds in both high yields and chemical purity directly to solution, from the solid phase support. |
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