Abstract: | An evaluation has been mde of the cardiotonic activities of cycloartane methylsteroids isolated from plants of the genusAstragalus and their synthetic analogs. It has been established that the compounds investigated exhibit a positive inotropic effect expressed to different degrees. The mechanism of the realization of the positive inotropic action of cycloartane glycosides differs from that of cardiosteroid drugs. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 510–514, July–August, 1994. |