New Thymol Derivate from Centipeda minima

1 Introduction Centipeda minima(Compositae) is an annual herbaceous plant found in moist places throughout the plains mainly in the southern regions of the People's Republic of China, Eastern tropical Asia, Australia and the Pacific Islandst[1,2]. It is a commonly used Chinese folk medicine for colds, whooping cough, nasal allergy, malaria and asthma[2]. A number of sesquiterpene lactones, flavonoids and triterpenes have previously been isolated from C. minima[2,3]. During our study on searching for biological active components from this plant, five compounds were isolated. Compound 1 was structurally elucidated as a new thymol derivate, and compounds 2, 3 and 4 were isolated from the plant for the first time.