An efficient and green method for the synthesis of [1,3]oxazine derivatives catalyzed by thiamine hydrochloride (VB1) in water |
| |
| Affiliation: | 1. Medicinal Chemistry Research Laboratory, School of Chemical Sciences, Solapur University, 413 255 Solapur, Maharashtra, India;2. Postgraduate Department and Research Centre, Padmashri Vikhe Patil College, 413 713 Pravaranagar, Maharashtra, India;3. Department of Chemistry, University of Mumbai, Ratnagiri sub-centre, 415 639 Ratnagiri, Maharashtra, India |
| |
| Abstract: | An efficient and convenient synthesis of 1,3-oxazine derivatives has been achieved by the one-pot, multicomponent condensation of α- or β-naphthol, an aniline and formaldehyde using thiamine hydrochloride (VB1) as a versatile biodegradable and reusable catalyst in water as a universal solvent. |
| |
| Keywords: | 1,3-oxazines Multicomponent reaction Aqueous medium |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
