| 新型含硫手性大环配体的合成 |
| |
| 引用本文： | 赵英,张小玲,等.新型含硫手性大环配体的合成[J].新疆大学学报(理工版),2001,18(3):319-333. |
| |
| 作者姓名： | 赵英 张小玲 |
| |
| 作者单位： | [1]新疆大学化学与化工学院，新疆乌鲁木齐830046 [2]四川教育学院化学系，四川成都610041 |
| |
| 摘 要： | 以L－半胱氨酸为手性源，合成了一类新型含硫手性大环配体，并进行了结构表征，L－半胱氨酸与二溴化合物反应生成双氨基酸，转变为双氨基酸酯后与双酰氯在高度稀释和无水条件下进行关环反应，制得含硫手性大环配体。
|
| 关 键 词： | L－半胱氨酸 含硫手性大环配体 合成 结构表征 仿生化学 双氨基酸 |
| 文章编号： | 1000-3839(2001)03-0319-05 |
| 修稿时间： | 2000年12月25 |
The Synthesis of Novel Sulfur-containing Chiral Macrocyclic Ligands |
| |
| ZHAO Ying\ ,ZHANG Xiao-ling\ ,LI Xing-shu\ ,XEI Ru-gang\.The Synthesis of Novel Sulfur-containing Chiral Macrocyclic Ligands[J].Journal of Xinjiang University(Science & Engineering),2001,18(3):319-333. |
| |
| Authors: | ZHAO Ying\ ZHANG Xiao-ling\ LI Xing-shu\ XEI Ru-gang\ |
| |
| Institution: | ZHAO Ying\ 1,ZHANG Xiao-ling\ 3,LI Xing-shu\ 2,XEI Ru-gang\ 3 |
| |
| Abstract: | The synthesis is performed of a novel sulfur-containing chiral macrocyclic ligands using L-cysteine as the source of chirality.The following is the synthetic method.In the presence of NaHCO\-3,L-cysteine reacts with dibromoalkane to form bridged bis-amino acids under a very mild condition,then,are transformed to the bis-esters and cyclized with bis-acid chlorides to give the target compounds 3a-3e.The structures proposed for these novel macrocycles are consistent with the data obtained from their\ 1HNMR,MS and IR spectra and elemental analysis. |
| |
| Keywords: | L-cysteine sulfur-containing chiral macrocyclic ligand synthesis characterization |
| 本文献已被 CNKI 维普 等数据库收录！ |
