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Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment
引用本文:GuangYaXIANG HeinerECKSTEIN. Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment[J]. 中国化学快报, 2004, 15(7): 768-770
作者姓名:GuangYaXIANG HeinerECKSTEIN
作者单位:[1]PharmacySchoolofTongjiMedicalCollege,HUST,Wuhan430030 [2]InstituteofOrganicChemistry,UniversityofTiibingen,Tiibingen,D-72076,Germany
摘    要:The enzymatic synthesis of a tetrapeptide Phac-Met-Gly-Trp-Met-OEt is reported. It was synthesized by coupling Phac-Met-OEt with Gly-OMe. HCI, Trp-OMe and Met-OEt successively, catalyzed by α-chymotrypsin, papain and α-chymotrypsin respectively. The results of FAB-MS showed that the products had the correct molecular mass.

关 键 词:CCK-8 四肽 酶合成 α-糜蛋白酶 木瓜蛋白酶

Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment
Guang Ya XIANG,Heiner ECKSTEINPharmacy School of Tongji Medical College,HUST,Wuhan Institute of Organic Chemistry,University of Tubingen,Tubingen,D-,Germany. Enzymatic Synthesis of a CCK-8 Tetrapeptide Fragment[J]. Chinese Chemical Letters, 2004, 15(7): 768-770
Authors:Guang Ya XIANG  Heiner ECKSTEINPharmacy School of Tongji Medical College  HUST  Wuhan Institute of Organic Chemistry  University of Tubingen  Tubingen  D-  Germany
Affiliation:Guang Ya XIANG,Heiner ECKSTEINPharmacy School of Tongji Medical College,HUST,Wuhan 430030 Institute of Organic Chemistry,University of Tubingen,Tubingen,D-72076,Germany
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