| Abstract: | An optimization procedure for multi-step temperature programmed capillary GC was investigated for the detailed hydrocarbon analysis of gasoline. A set of twelve responses, represented by the value of the resolution of the most difficult separations, was selected from several isothermal analyses. The variation of these responses versus the temperature programming conditions was then modeled using a Doehlert matrix for experimental design. Optimal experimental conditions for the twelve responses were then obtained from a response surface optimization. The predicted and experimental resolutions were in good agreement. |
