Stereoselective approaches to 2,3,6-trisubstituted piperidines. An enantiospecific synthesis of quinolizidine (-)-217A |
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| Authors: | Mancey Nicole C Sandon Nicolas Auvinet Anne-Laure Butlin Roger J Czechtizky Werngard Harrity Joseph P A |
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| Affiliation: | Department of Chemistry, University of Sheffield, Sheffield, UK. |
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| Abstract: | The enantiospecific and diastereocontrolled total synthesis of alkaloid (-)-217A is described that employs a stepwise [3+3] annelation strategy and a piperidine 2,3-cyclopropanation-ring opening reaction as the key steps. |
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