Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus |
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| Authors: | Yin Sheng Xue Jun-Juan Fan Cheng-Qi Miao Ze-Hong Ding Jian Yue Jian-Min |
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| Affiliation: | State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, PR China. |
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| Abstract: | Eucalyptals A-C (1-3) with a new skeleton of 3,5-diformyl-isopentyl phloroglucinol-coupled cadinane were isolated from the fruits of Eucalyptus globulus. Their structures were elucidated by spectroscopic analysis, and that of 1 was confirmed by single-crystal X-ray diffraction. The biosynthetic pathway of 1-3 was also postulated. Compounds 1-3 exhibited selective cytotoxicity against the HL-60 cell line. |
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