Dual‐Physical Cross‐Linked Tough and Photoluminescent Hydrogels with Good Biocompatibility and Antibacterial Activity

Development of novel photoluminescent hydrogels with toughness, biocompatibility, and antibiosis is important for the applications in biomedical field. Herein, novel tough photoluminescent lanthanide (Ln)‐alginate/poly(vinyl alcohol) (PVA) hydrogels with the properties of biocompatibility and antibiosis have been facilely synthesized by introducing hydrogen bonds and coordination bonds into the interpenetrating networks of Na‐alginate and PVA, via approaches of frozen‐thawing and ion‐exchanging. The resultant hydrogels exhibit high mechanical strength (0.6 MPa tensile strength, 5.0 tensile strain, 6.0 MPa compressive strength, and 900 kJ m^?3 energy dissipation under 400% stretch), good photoluminescence as well as biocompatibility and antibacterial activity. The design strategy provides a new avenue for the fabrication of multifunctional photoluminescent hydrogels based on biocompatible polymers.