首页 | 本学科首页   官方微博 | 高级检索  
     检索      


The synthesis of some 4H-pyrimido[2,1-b]benzothiazol-4-ones
Authors:Robert J Alaimo
Abstract:A series of 8-substituted and 7,8-disubstituted-4-oxo-3-(4H-pyrimido2,1-b]benzothiazole)carboxylic acids and esters including a 9-aza analog were synthesized from substituted 2-aminobenzothiazoles and diethyl ethoxymethylenemalonate. The 9-aza analog, ethyl 8-methoxy-4-oxo-3-(4H-pyrido3′,2′:4,5]thiazolo3,2-a]pyrimidine)carboxylate ( 56 ), represents the first preparation of this new heterocyclic ring. These compounds were examined for antiparasitic activity, however, no significant activity was detected.
Keywords:
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号