Two New, 1‐Oxygenated ent‐Kaurane‐Type Diterpenes from Croton kongensis |
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| Authors: | Wei Chen Xiao‐Dong Yang Jing‐Feng Zhao Hong‐Bin Zhang Liang Li |
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| Affiliation: | 1. Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, School of Chemical Science and Teleology, Yunnan University, Kunming 650091, P.?R. China, (phone: +86‐871‐5033644‐8899;2. fax: +86‐871‐5035538);3. Institute of Material Medica, Yangtze River Pharmacy Group, No.?1 South Yangtze River Road, Taizhou 225321, P.?R. China |
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| Abstract: | One new ent‐8,9‐secokaurane diterpene, kongensin D ( 1 ), and one new ent‐kaurane diterpene, kongensin E ( 2 ), along with one known compound, (7α)‐7,18‐dihydroxy‐ent‐kaur‐16‐en‐15‐one 18‐acetate ( 3 ), were isolated from the aerial parts of Croton kongensis. The structures of the new compounds were elucidated by means of HR‐MS and in‐depth NMR experiments, and by comparison with literature data. Compounds 1 and 2 showed an unusual oxygenation pattern with an OH or AcO group at C(1). |
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| Keywords: | Croton kongensis Diterpenes ent‐Kaurane Kongensins D and E |
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