Total Synthesis of a Natural Cerebroside from Euphorbiaceae |
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Authors: | Francesca Cateni Marina Zacchigna Jelena Zilic Gabriella Di Luca |
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Institution: | 1. Department of Pharmaceutical Sciences, University of Trieste, P.zle Europa 1, I‐34127 Trieste, (phone: +?39‐040‐5583720;2. fax: +?39‐040‐52572) |
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Abstract: | The regioselective total synthesis of the natural cerebroside (2R,15Z)‐N‐{(1S,2S,3R,4R,5Z)‐1‐(β‐D ‐glucopyranosyloxy)methyl]‐2,3,4‐trihydroxyheptadec‐5‐en‐1‐yl}‐2‐hydroxytetracos‐15‐enamide ( 2 ), originally isolated from Euphorbiaceae, is reported in full detail. |
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Keywords: | Cerebroside Euphorbia species Sphingosine Lipids Sphingoglycolipids |
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