Further Daphniphyllum Alkaloids from the Leaves of Daphniphyllum macropodum Miq. |
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| Authors: | Zhen‐Yu Li Ping Chen Hong‐Gui Xu Shu‐Ying Peng Yi‐Ming Yang Zhong‐Zhen Zhao Yue‐Wei Guo |
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| Institution: | 1. State Key Laboratory of Drug Research, Institute of Materia Medica, Chinese Academy of Science, Zu Chong Zhi Road 555, Shanghai 201203, P.?R. China, (phone: +86‐21‐50805813);2. School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong 999077, P.?R. China |
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| Abstract: | Five new polycyclic Daphniphyllum alkaloids, macropodumines F ( 1 ) and G ( 2 ), 17‐oxoyuzurimine ( 3 ), and macropodumines H ( 4 ) and I ( 5 ), were isolated from the leaves of D. macropodum Miq ., collected in Sichuan Province, China. The structures and relative configurations of the new compounds – as well as of four known, related alkaloids – were elucidated on the basis of in‐depth spectroscopic and mass‐spectrometric analyses, by chemical derivatization, and by comparison of spectroscopic data with those of known compounds. |
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| Keywords: | Daphniphyllum macropodum Alkaloids Macropodumines F – I Yuzurimine 17‐oxo‐ |
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