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Capacitive Sensing of Amino Acids Using Caliraxene‐Coated Silicon Transducers
Authors:Vijaykumar Ijeri  Francis Vocanson  Claude Martelet  Nicole Jaffrezic‐Renault
Institution:1. CEGELY, Ecole Centrale de Lyon, Ecully cedex 69134, France;2. Present address: University of Aarhus, Department of Chemistry, Langelandsgade 140, DK 8000, Aarhus C, Denmark;3. LACE, UMR CNRS 5634, Université Lyon I,Villeurbanne 69622, France
Abstract:The possibility of using capacitance and flat band voltage as measurable quantities for determining amino acids that are neither electroactive nor with strong UV‐vis absorption has been explored. The sensors were fabricated by immobilizing calixarene derivatives on Si/SiO2/Si3N4 transducers. The measurements were made in sulfuric acid media of ca. pH 1 and in physiological buffer of pH 7.4. The different calixarene derivatives showed varying sensitivities to the amino acids ranging from 8 to 137 mV/decade.
Keywords:Calixarene  Amino acids  Capacitance  Silicon transducers
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