The NADH Electrochemical Detection Performed at Carbon Nanofibers Modified Glassy Carbon Electrode |
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| Authors: | Adina Arvinte Federica Valentini Antonio Radoi Fabiana Arduini E Tamburri Lucian Rotariu Giuseppe Palleschi Camelia Bala |
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| Institution: | 1. Laboratory of Quality Control and Process Monitoring, Faculty of Chemistry, University of Bucharest, 4‐12 Regina Elisabeta Blvd., 030018?Bucharest, Romania;2. Dipartimento di Scienze e Tecnologie Chimiche, Universitá degli Studi di Roma, Tor Vergata, via della Ricerca Scientifica 1, 00133?Roma, Italy |
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| Abstract: | In this work, the capability of carbon nanofibers to be used for the design of catalytic electrochemical biosensors is demonstrated. The direct electrochemistry of NADH was studied at a glassy carbon electrode modified using carbon nanofibers. A decrease of the oxidation potential of NADH by more than 300 mV is observed in the case of the assembled carbon nanofiber‐glassy carbon electrode comparing with a bare glassy carbon electrode. The carbon nanofiber‐modified electrode exhibited a wide linear response range of 3×10?5 to 2.1×10?3 mol L?1 with a correlation coefficient of 0.997 for the detection of NADH, a high specific sensitivity of 3637.65 (μA/M cm2), a low detection of limit (LOD=3σ) of 11 μM, and a fast response time (3 s). These results have confirmed the fact that the carbon nanofibers represent a promising material to assemble electrochemical sensors and biosensors. |
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| Keywords: | Carbon nanofibers (CNFs) Chemically modified electrodes (CMEs) NADH direct electrochemistry Biosensor |
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