1. Centre of Chemistry, University of Minho, Gualtar, P‐4710‐057 Braga, Portugal, Tel +351253604386;2. Fax + 351253678983
Abstract:
A simple and efficient method was developped for the synthesis of 3‐(5‐amino‐4‐cyano‐1H‐imidazol‐1‐yl)‐4‐substituted benzoic acids 3 . These compounds were isolated by intramolecular cyclisation of the corresponding 3‐{(Z)‐2‐amino‐1,2‐dicyano‐vinyl]amino}methyleneaminobenzoic acids in the presence of base.