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Electrocatalytic Oxidation and Determination of Dopamine in the Presence of Ascorbic Acid and Uric Acid at a Poly (4‐(2‐Pyridylazo)‐Resorcinol) Modified Glassy Carbon Electrode
Authors:Jinghua Chen  Jing Zhang  Xinhua Lin  Hongyan Wan  Shaobo Zhang
Affiliation:1. Department of Analytical Chemistry and Pharmaceutical Analysis, Fujian Medical University, Fuzhou 350004, P.?R. China;2. Pharmaceutical Department of Fujian College of Medical Occupation and Technology, Fuzhou 350101, P.?R. China
Abstract:A sensitive and selective electrochemical method for the determination of dopamine (DA) was developed using a 4‐(2‐Pyridylazo)‐Resorcinol (PAR) polymer film modified glassy carbon electrode (GCE). The PAR polymer film modified electrode shows excellent electrocatalytic activity toward the oxidation of DA in a phosphate buffer solution (PBS) (pH 4.0). The linear range of 5.0×10?6–3.0×10?5 M and detection limit of 2.0×10?7 M were observed. Simultaneous detection of AA, DA and UA has also been demonstrated on the modified electrode. This work provides a simple and easy approach to selective detection of DA in the presence of AA and UA.
Keywords:Poly‐PAR modified GCE  Electrocatalysis  DA  UA  AA
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