A New Pregnane and a New Diphenylmethane from the Root Barks of Periploca sepium |
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| Authors: | Lei Wang Zhi‐Qi Yin Wen‐Bin Shen Qing‐Wen Zhang Wen‐Cai Ye |
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| Institution: | 1. Department of Phytochemistry, China Pharmaceutical University, Nanjing 210038, P.?R. China, (phone: +86‐25‐8532‐2132;2. fax: +86‐25‐8530‐1528);3. Center of Instrumental Analysis, China Pharmaceutical University, Nanjing 210009, P.?R. China;4. Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau, P.?R. China;5. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, P.?R. China |
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| Abstract: | A new polyoxygenated pregnane genin and a new diphenylmethane, along with five known pregnane derivatives, were isolated from the root barks of Periploca sepium. The structures of the new compounds were elucidated as (3β,14β)‐3,14‐dihydroxy‐21‐methoxypregn‐5‐en‐20‐one ( 1 ) and 2‐hydroxy‐5‐(2‐hydroxy‐4‐methoxybenzyl)‐4‐methoxybenzaldehyde ( 2 ) on the basis of spectroscopic methods, especially 2D‐NMR and MS analyses. The known compounds were identified by comparing their physical and spectroscopic data with those reported in the literature. |
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| Keywords: | Pregnanes Periploca sepium Methanes diphenyl‐ |
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