Three New Clerodane Diterpenoids from the Bulbils of Dioscorea bulbifera L. var. sativa |
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| Authors: | Rémy?Bertrand Teponno Azefack?Léon Tapondjou Hyun Ju‐Jung Jung‐Hwan Nam Pierre Tane Hee‐Juhn Park |
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| Institution: | 1. Department of Chemistry, Faculty of Science, University of Dschang, Box 183, Dschang, Cameroon, (phone: +237‐5004826;2. fax: +237‐3451202);3. Division of Applied Plant Sciences, Sangji University, Wonju 220‐702, Korea |
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| Abstract: | From the bulbils of Dioscorea bulbifera L. var. sativa, three new clerodane diterpenoids, bafoudiosbulbin C (=methyl (2β,8α,12S)‐17‐oxo‐2,19 : 8,19 : 12,17 : 15,16‐tetraepoxycleroda‐3,13(16), 14‐triene‐18‐carboxylate; 1 ), bafoudiosbulbin D (=methyl (2β,6β,12R)‐17,19‐dioxo‐2,19 : 6,17 : 8,12 : 15,16‐tetraepoxycleroda‐13(16),14‐diene‐18‐carboxylate; 2 ), and bafoudiosbulbin E (=methyl (2β,3α,4α,6β,12R)‐17,19‐dioxo‐2,19 : 3,4 : 6,17 : 8,12 : 15,16‐pentaepoxycleroda‐13(16),14‐diene‐18‐carboxylate; 3 ) were isolated, together with the known compounds bafoudiosbulbins A and B, 3‐O‐β‐D ‐glucopyranosyl‐β‐sitosterol, and 6′‐stearoyl‐3‐O‐β‐D ‐glucopyranosyl‐β‐sitosterol. Their structures were established by high‐field NMR techniques (1H,1H‐COSY, 13C‐DEPT, HSQC, HMBC, and NOESY), MS analyses, as well as by comparison of their spectral data with those of related compounds. |
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| Keywords: | Dioscorea bulbifera Clerodane diterpenoids Diterpenoids Bafoudiosbulbins C– E |
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