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Diterpenoid Alkaloids of Delphinium buschianum Grossh.
Authors:Leyla Bitiş  Sevda Süzgeç  Ulaş Sözer  Hasan Özçelik  Josef Zapp  Alexandra K Kiemer  Filiz Meriçli  Ali H Meriçli
Institution:1. Marmara University, Faculty of Pharmacy, Department of Pharmacognosy, 34668 Haydarpasa, Istanbul, Turkey;2. Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, 34116 Beyaz?t, Istanbul, Turkey (phone: +90‐212‐4400268);3. Süleyman Demirel University, Faculty of Science and Literature, Department of Biology, Isparta, Turkey;4. Saarland University, Institute of Pharmaceutical Biology, P.O. Box 151150, D‐66041 Saarbrücken, Germany
Abstract:From the aerial parts of Delphinium buschianum Grossh ., collected in Turkey, a new diterpenoid alkaloid 1 , named budelphine, was isolated along with the known diterpenoid alkaloids karakoline ( 2 ), 18‐hydroxy‐14‐O‐methylgadesine ( 3 ), delsoline ( 4 ), lapaconidine ( 5 ), columbianine ( 6 ), 14‐benzoylneoline ( 7 ), and hetisine ( 9 ). The structure of 1 was established on the basis of 1H‐, 13C‐, DEPT, 1H,1H‐COSY, NOESY, HSQC, and HMBC NMR studies.
Keywords:Delphinium buschianum  Diterpenoid alkaloids  Alkaloids  Budelphine
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