脂肪酸光脱羧酶及其在有机合成中应用的研究进展

生物基脂肪酸是极具应用潜力的可再生资源。以绿色、低碳的方式对生物基脂肪酸进行转化合成高价值的化学品和燃料可满足现代社会可持续发展的迫切需要，也符合绿色生物制造的需求。生物催化因反应条件温和、选择性高等特点受到众多学者的广泛关注，其中，近年来新发现的由可见光驱动的脂肪酸光脱羧酶（fatty acid photodecarboxyase, CvFAP）可催化不同链长的脂肪酸进行脱羧反应用来合成燃料和化学品，反应过程具有极高原子经济性，在绿色催化工艺及能源领域具有广阔的应用前景。本综述旨在对脂肪酸光脱羧酶（CvFAP）的最新研究进展进行总结分析，并对脂肪酸光脱羧酶的发展趋势进行展望，以期为脂肪酸光脱羧酶（CvFAP）在绿色合成领域的进一步开发利用提供参考。

Research progress of fatty acid photodecarboxylase in the synthesis of aviation fuels and organic molecules

Bio-based fatty acids are renewable energy with great application potential. The conversion of bio-based fatty acid raw materials into high-value chemicals and fuels in a green and low-carbon way can meet the urgent needs of sustainable development in modern society, and also meet the needs of green biological manufacturing. Biocatalysis has attracted extensive attention from many scholars due to its mild reaction conditions and high selectivity. Among them, the newly discovered visible light-driven fatty acid photodecarboxylase (CvFAP) can catalyze the decarboxylation of fatty acids with different chain lengths to synthesize fuels and chemicals. The reaction process has an extremely high atomic economy and has broad application prospects in the field of green catalytic technology and energy. This review aims to summarize and analyze the latest research progress of fatty acid photodecarboxylase (CvFAP) and prospects for the development trend of fatty acid photodecarboxylase, to provide references for the further development and utilization of fatty acid photodecarboxylase (CvFAP) in the field of green synthesis.