| 基于MEMS微针技术的研究现状与展望 |
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| 引用本文： | 许宝建,金庆辉,赵建龙.基于MEMS微针技术的研究现状与展望[J].微纳电子技术,2005,42(4):150-156. |
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| 作者姓名： | 许宝建 金庆辉 赵建龙 |
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| 作者单位： | 中国科学院上海微系统与信息技术研究所生物芯片实验室,上海,200050 |
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| 基金项目： | 中国科学院创新知识工程重要方向性项目(KGCX2-SW-108) |
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| 摘 要： | 基于MEMS的微针技术研究是当前药物传输领域中的热点。随着微细加工技术的发展,微针技术及其应用得到了快速发展,除了向生物体内传输药物和向细胞内传输DNA外,还可以用来监测和反馈药物对生物体的影响及外源DNA在受体内的表达形式,同时在植入式器械方面也有所发展。本文综述了基于MEMS微针技术及应用的发展状况。
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| 关 键 词： | 微针 药物传输 基因传输 微电子机械系统 |
| 文章编号： | 1671-4776(2005)04-0150-07 |
| 修稿时间： | 2004年10月29 |
An Review of MEMS-Based Microneedles Technology Developments |
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| XU Bao-jian,JIN Qing-hui,ZHAO Jian-long.An Review of MEMS-Based Microneedles Technology Developments[J].Micronanoelectronic Technology,2005,42(4):150-156. |
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| Authors: | XU Bao-jian JIN Qing-hui ZHAO Jian-long |
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| Abstract: | Research of MEMS-based microneedles is a very important project in drug and gene delivery. Recently,the technologies and applications of microneedles have made rapid progress with the development of microfabrication technologies. They can be used to introduce agents into tissues and monitor the effects of injected agents on tissues. And they are utilized to transfer DNA into cells and detect the expressions of foreign DNA in receiptor. Furthermore,microneedle is developed for embedded apparatus in drug and gene delivery systems. In this paper,we review recent progress in the technologies and applications of MEMS-based microneedle. |
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| Keywords: | microneedle drug delivery gene delivery MEMS |
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