Protein microarrays for diagnostic assays |
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Authors: | Michael Hartmann Johan Roeraade Dieter Stoll Markus F Templin Thomas O Joos |
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Institution: | (1) School of Chemical Science and Engineering, Department of Analytical Chemistry, Royal Institute of Technology, 10044 Stockholm, Sweden;(2) NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770 Reutlingen, Germany |
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Abstract: | Protein microarray technology has enormous potential for in vitro diagnostics (IVD). Miniaturized parallelized immunoassays
are perfectly suited to generating a maximum of diagnostically relevant information from minute amounts of sample whilst only
requiring small amounts of reagent. Protein microarrays have become well-established research tools in basic and applied research
and the first products are already on the market. This article reviews the current state of protein microarrays and discusses
developments and future demands relating to protein arrays in their role as multiplexed immunoassays in the field of diagnostics.
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Keywords: | Protein microarrays Multiplexed diagnostics In-vitro diagnostics Focused protein-profiling Analytical microarrays |
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