A convenient and versatile approach to 2,3-dihydro-4H-pyran-4-ones via tandem aldol reaction-conjugate addition |
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Authors: | Bo Gao Zhengyan Fu |
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Institution: | a Key Laboratory of Green Chemistry and Technology (Sichuan University), Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China b State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China |
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Abstract: | Aldol reaction of enones 1a-c with aldehydes followed by intramolecular conjugate addition proceeded smoothly to afford corresponding 2,3-dihydro-4H-pyran-4-ones in high yields under mild conditions. |
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