Enantioselective Michael additions on α,β-unsaturated N-acylated oxazolidin-2-ones using mild scandium triflate catalysis |
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| Authors: | Sami J.K. Sauerland Ari M.P. Koskinen |
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| Affiliation: | a Laboratory of Organic Chemistry, Helsinki University of Technology, PO Box 6100, FI-02015 TKK, Finland
b PCAS Finland Oy, PO Box 979, FIN-20101 Turku, Finland |
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| Abstract: | The asymmetric conjugate addition of thiophenol to (E)-3-crotonoyloxazolidin-2-one catalysed by the scandium(III) triflate complex of Ph-PYBOX gave the corresponding adduct in 66% ee. Lanthanoid triflates gave lower enantioselectivities (?28% ee). |
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| Keywords: | Scandium triflate Michael addition α,β-Unsaturated ester N-acylated oxazolidin-2-ones |
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