Microwave-assisted solvent-free and catalyst-free Kabachnik-Fields reactions for α-amino phosphonates |
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| Authors: | Xue-Jun Mu Jian-Ping Zou Wei Zhang |
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| Institution: | a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering, Suzhou University, 1 Shizi St. Suzhou 215006, Jiangsu, China
b Fluorous Technologies, Inc., University of Pittsburgh Applied Research Center, 970 William Pitt Way, Pittsburgh, PA 15238, USA |
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| Abstract: | A highly efficient solvent-free and catalyst-free method for the synthesis of α-amino phosphonates is developed by a microwave-assisted three-component Kabachnik-Fields reaction involving aldehyde, amine, and dimethyl phosphite. |
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