Regioselective synthesis of 1-hydroxycarbazoles via anionic [4+2] cycloaddition of furoindolones: a short synthesis of murrayafoline-A |
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| Authors: | D Mal B Senapati P Pahari |
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| Institution: | Department of Chemistry, Indian Institute of Technology, Kharagpur 721 302, India |
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| Abstract: | Suitably N-protected furoindolones react regioselectively with a variety of Michael acceptors in the presence of LDA to give 1-hydroxycarbazoles in a single-pot process and in good yields. The methodology has been applied to the synthesis of murrayafoline-A. |
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| Keywords: | Carbazole Cycloaddition Furoindolone Murrayafoline-A |
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