Kehokorins A-C, novel cytotoxic dibenzofurans isolated from the myxomycete Trichia favoginea var. persimilis |
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| Authors: | Kouken Kaniwa Yukinori Yamamoto |
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| Institution: | a Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 263-8522, Japan
b Graduate School of Pharmaceutical Sciences, Chiba University, 1010-53 Ohtsu-ko, Kochi 781-5102, Japan |
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| Abstract: | Kehokorins A (1)-C (3), three novel dibenzofurans, have been isolated from field-collected fruit bodies of the myxomycete, Trichia favoginea var. persimilis, and their structures were elucidated by spectral data. Kehokorin A (1) was a α-l-rhamnopyranoside of kehokorin B (2), while kehokorin C (3) was a 1-demethoxy analog of 2. Kehokorin A (1) was cytotoxic against HeLa cells with an IC50 value of 1.5 μg/mL. |
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| Keywords: | Myxomycete Trichia favoginea var persimilis Dibenzofuran Fruit body Cytotoxicity |
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