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Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles in ionic liquid/water system
Authors:Ya-Bin Zhao
Affiliation:State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
Abstract:A copper(I) catalyst in a mixture of the ionic liquid [bmim][BF4] and water, can effect three-component reaction of halides, sodium azide and alkynes to form 1,4-disubstituted 1,2,3-triazoles in good to high yields. The method is efficient and environmentally friendly.
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