Efficient synthesis of 1,4-disubstituted 1,2,3-triazoles in ionic liquid/water system |
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Authors: | Ya-Bin Zhao |
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Affiliation: | State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China |
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Abstract: | A copper(I) catalyst in a mixture of the ionic liquid [bmim][BF4] and water, can effect three-component reaction of halides, sodium azide and alkynes to form 1,4-disubstituted 1,2,3-triazoles in good to high yields. The method is efficient and environmentally friendly. |
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