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An efficient and clean synthesis of bis(indolyl)methanes in a protic solvent at room temperature
Authors:Mohit L Deb
Institution:Medicinal Chemistry Division, Regional Research Laboratory, Jorhat 785 006, Assam, India
Abstract:Electrophilic substitution reactions of indoles with various aldehydes were carried out in a protic solvent at room temperature in the absence of any other catalyst to afford bis(indolyl)-methanes in excellent yields.
Keywords:Indoles  Bis(indolyl)methanes  Aldehydes  Protic solvent  Aqueous medium
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