Organocatalytic asymmetric conjugate addition of thioacetic acid to β-nitrostyrenes |
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| Authors: | Hao Li |
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| Affiliation: | Department of Chemistry, MSC03 2060, University of New Mexico, Albuquerque, NM 87131-0001, USA |
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| Abstract: | A method for organocatalytic, enantioselective Michael addition reactions of thioacetic acid with a range of trans-β-nitrostyrenes has been developed. The processes, promoted by the chiral amine thiourea organocatalyst, take place in high yields with up to 70% ee. |
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| Keywords: | Amine thiourea Asymmetric organocatalysis Michael addition reaction Nitroolefins Thioacetic acid |
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