Regioselective Suzuki coupling of benzofuran or benzothiophene boronic acids and dibromo substituted naphthalenes: synthesis of a potent inhibitor of plasminogen activator inhibitor-1 |
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| Authors: | Zheng Wang Hassan Elokdah Geraldine McFarlane Sherry Pan Madelene Antane |
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| Institution: | Chemical and Screening Sciences, Wyeth Research, CN 8000, Princeton, NJ 08543, USA |
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| Abstract: | An efficient route to the biologically active naphthyl benzofuran derivative is described. The synthesis highlights a regioselective Suzuki coupling of a benzofuran and a dibromo substituted naphthalene. The scope of regioselective Suzuki coupling has been investigated. |
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