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Ring-rearrangement metathesis of bicyclic amino acid derivatives
Authors:Simon Maechling  John E. McKendrick  Sandeep Basra  Siegfried Blechert
Affiliation:a School of Chemistry, The University of Reading, Whiteknights, Reading RG6 6AD, UK
b Technische Universität Berlin, Strasse des 17. Juni 135, 10623 Berlin, Germany
Abstract:In this letter, we describe the ring-rearrangement metathesis (RRM) of bicyclic amino acid derivatives. The procedure is of use for the synthesis of constrained amino acid and peptide derivatives with potential as reverse-turn inducers.
Keywords:Metathesis   Amino acids   Peptides   Peptidomimetics
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