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A cationic tetrahedral chromophore for amplified DNA detection |
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| Authors: | Parameswar K. Iyer Shu Wang |
| Affiliation: | a Department of Chemistry and Institute of Polymers and Organic Solids, University of California, Santa Barbara, CA 93106, USA b Department of Chemistry, Indian Institute of Technology Guwahati, North Guwahati-781039, Assam, India c Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, PR China |
| Abstract: | The tetrahedral cationic chromophore, tetrakis [4-(9,9-bis(6′-(N,N,N-trimethylammonium)hexyl)-2-fluorenyl)phenyl]methane (1) shows better fluorescence resonance energy transfer (FRET) to the fluorescein (Fl) attached to the 5′-terminus of double-stranded DNA (dsDNA-Fl) as compared to the linear oligomers 2 and 3 and also provides efficient DNA hybridization detection. |
| Keywords: | Tetrahedral chromophores FRET DNA detection |
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