Mathematical modeling of bacterial metabolism |
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Authors: | A. N. Golomysova M. Gomelsky P. S. Ivanov |
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Affiliation: | 1.Department of Biophysics, Faculty of Physics,Moscow State University,Moscow,Russia;2.Department of Molecular Biology,University of Wyoming,Laramie,USA |
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Abstract: | A variant of mathematical model construction for the anaerobic metabolism of a purple nonsulfur bacterium based on a flux balance analysis is presented in this paper. The model includes all the central metabolic pathways of the bacterial cell, as well as pathways for biosynthesis of amino acids and bacteriochlorophyll. It is shown that the results of modeling of bacterial photoheterotrophic growth on acetate agree with experimental values for the known metabolite pathways, which shows that the constructed model adequately describes actual cellular processes. |
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