Rarefaction on natural compound extracts diversity among genus |
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| Affiliation: | 1. Technical University of Cluj-Napoca, 28 Memorandumului, 400144 Cluj-Napoca, Cluj, Romania;2. University of Agricultural Science and Veterinary Medicine Cluj-Napoca, 3-5 Calea Mănăştur, 400372 Cluj-Napoca, Romania;3. “Iuliu Haţieganu” University of Medicine and Pharmacy Cluj-Napoca, Department of Medical Informatics and Biostatistics, 6 Louis Pasteur, 400349 Cluj-Napoca, Cluj, Romania;1. Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;2. Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand;3. Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;1. Center for Advanced Photonics Research, Temple University, Philadelphia, PA 19122, United States;2. Department of Chemistry, Temple University, Philadelphia, PA 19122, United States;3. Department of Physics, Temple University, Philadelphia, PA 19122, United States;4. Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen Ø, Denmark;1. Deutsches Zentrum für Luft- und Raumfahrt e.V., Institute of Space Systems, Bremen, Germany;2. Delft University of Technology, Chair of Space Systems Engineering, Delft, The Netherlands;1. Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali-3814, Bangladesh;2. Department of Physiology, Biochemistry and Pharmacology, Chittagong Veterinary and Animal Sciences University, Chittagong, Bangladesh;3. Department of Pharmacy, Atish Dipankar University of Science and Technology, Banani, Dhaka, Bangladesh;1. Faculty of Mathematics and Informatics, University of Sofia “St. Kliment Ohridski”, 5 James Bourchier Blvd., 1164 Sofia, Bulgaria;2. Bioinformatics Group, AgroBio Institute, 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria |
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| Abstract: | The aim of our study was to investigate the intrinsic diversity of genus based on chemical composition of natural extracts of Cacalia, Dracocephalum, Jatropha, Saussurea and Senecio. Four rarefaction approaches (richness, Shannon's entropy, Simpson's diversity, and max-entropy) were implemented as an algorithm and run 10,000 times. Our results showed similar patterns of richness in natural compounds according to genus and of Simpson's diversity index while max-entropy has a similar pattern as Shannon's entropy. The analysis of both richness in active compounds and weight of most frequent extracted compound revealed that Dracocephalum genus is most suitable for propagation. |
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| Keywords: | Biodiversity Bootstrap Rarefaction Compounds richness |
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