Rhenium(IV) compounds inducing apoptosis in cancer cells |
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| Authors: | Martínez-Lillo José Mastropietro Teresa F Lappano Rosamaria Madeo Antonio Alberto Marta E Russo Nino Maggiolini Marcello De Munno Giovanni |
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| Institution: | Centro di Eccellenza CEMIF.CAL, Dipartimento di Chimica, Università della Calabria, via P. Bucci 14/c, 87030 Arcavacata di Rende, Cosenza, Italy. |
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| Abstract: | The anticancer properties of a series of mononuclear Re(IV) compounds of formula ReCl(4)L (where L is bpy = 2,2'-bipyridine; bpym = 2,2'-bipyrimidine; dmbpy = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) were investigated for the first time. All compounds displayed potent in vitro antiproliferative activity against selected cancer cells. |
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