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冠状动脉斑块与血浆血管性血友病因子相关性临床研究
引用本文:刘玉和,徐丽华.冠状动脉斑块与血浆血管性血友病因子相关性临床研究[J].北华大学学报(自然科学版),2005,6(3):243-244.
作者姓名:刘玉和  徐丽华
作者单位:北华大学,医学院,吉林,吉林,132013;北华大学,附属医院,吉林,吉林,132011
摘    要:目的通过测定冠状动脉造影,显示不同粥样硬化斑块形态患者血浆血管性血友病因子(vWF)水平,从而探讨其临床意义.方法 62例接受冠状动脉造影患者分为不稳定斑块组(n=32)、稳定斑块组(n=11)和正常对照组(n=19).所有患者均于冠状动脉造影前采血测定血浆vWF水平.结果不稳定斑块组血浆vWF明显高于稳定斑块组,有显著性差异.结论血浆vWF水平高于稳定斑块组,可作为判定冠状动脉是否存在不稳定病变的间接参考.

关 键 词:冠状动脉疾病  冠状血管造影  血管性血友病因子
文章编号:1009-4822(2005)03-0243-02
修稿时间:2005年1月10日

Clinical Study on the Correlation between Coronary Atheroslerosis Plaque and Plasma of Von Willebrand Factor
LIU Yu-he,XU Li-hua.Clinical Study on the Correlation between Coronary Atheroslerosis Plaque and Plasma of Von Willebrand Factor[J].Journal of Beihua University(Natural Science),2005,6(3):243-244.
Authors:LIU Yu-he  XU Li-hua
Abstract:ObjectiveTo investigate the association of coronary atheroslerosis plaque with the plasma levels of von Willebrand factor(vWF).MethodsSixty-two patients undergoing selective coronary angiography were divided into 3 groups based on the plaque morphology. Group V(n=32), Group H(n=11), Group N(n=19). The plasma level of vWF were determined by enzyme-linked immunosobent assay (ELISA) before angiography.ResultsThe plasma level of vWF in group V was significantly higher than that of group H.ConclusionPlasma levels of vWF can be a predictive marker for the judgement of unstable lesions of coronary atheroslerosis.
Keywords:Coronary disease  Angiography  Von Willebrand factor
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