Application of dearomatization strategy on the synthesis of furoquinolinone and angelicin derivatives |
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| Authors: | Ye Yang Zhang Li Fan Renhua |
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| Affiliation: | Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, 200433, China. |
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| Abstract: | The oxidative dearomatization of 3-(3-alkynyl-4-hydroxyphenyl)propanoic acid is combined with a cascade transition-metal catalyzed cyclization/addition/aromatization/lactamization sequence, which provides a novel approach to prepare furoquinolinone and angelicin derivatives in a convergent and efficient manner. |
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