Synthesis of 2-Propargylaminoethanols from α,β-acetylenic aldimines |
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| Authors: | M V Karpov A V Khramchikhin I V Suvorova Yu L Piterskaya M D Stadnichuk |
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| Institution: | (1) St. Petersburg Institute of Technology, Moskovskii pr. 26, St. Petersburg, 198013, Russia |
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| Abstract: | A method of synthesis of 2-propargylaminoethanols, perspective synthons for a one-pot synthetic technology excluding isolation of unstable prop-2-ynylideneaminoethanols is developed. A number of 2-propargylaminoethanol hydrochloride derivatives are synthesized, and their 1H and 13C NMR spectra were discussed. |
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