PSP对癌症病人化/放疗毒性反应的数据统计分析

按WHO抗癌药急性及亚急性毒性分级标准 ,对 650例化、放疗肿瘤患者分别作了治疗前后毒性反应的总分值统计。结果加服PSP组 ( 557例 )的疗后总分值为837,低于疗前的 962 ;而 93例阳性对照组 (加服鲨肝醇 )疗前总分为 157,疗后为 2 4 1,疗后总分高于疗前。用Wilcoxon两样本秩和统计法检验 ,PSP组和对照组间具有极显著差异 ,表明PSP对比、放疗药物引起的毒副反应有明显降低效应。

Statistical Analysis of the Lowering Effects of PSP on the Toxic and Side Effects of Chemo-and Radio-Therapy of Cancers

s:The total score of toxic effects of 650 cases of cancer patients were made respectively before and after chemo and radio therapy according to the graded standards of acute and sub acute toxicity of anticancerous drugs specified by WHO. The result showed that integral values after therapy of 557 cases taking PSP was 837. It was lower than 962 before therapy; While the integral values of 93 cases of positive control group (taking butylalcohol) before therapy was 157 and after therapy was 241. The total scok after therapy was higher than that before therapy. Tested by means of Wilcoxon’s rank sun statistic of the two sample, the difference between PSP group and the control group was marked. This showed that PSP has marked lowering effects on the toxic and side effects caused by chemo and radio therapeutic drugs.