N-hydroxypeptides. I. Preparation of N-benzyloxy-α-amino acid anhydrides and their use in peptide synthesis |
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| Authors: | Masayasu Akiyama Masayoshi Hasegawa Haruyuki Takeuchi Kazuyuki Shimizu |
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| Institution: | Department of Industrial Chemistry, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184, Japan |
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| Abstract: | N-Benzyloxy-DL-α-amino acids are transformed with phosgen to N-benzyloxy-DL-α-amino acid anhydrides which react smoothly with the amino component of peptides to give the corresponding N-benzyloxypeptides. |
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