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Ring transformation of 4-oxo-1,6,7,8-tetrahydro-4H-pyrido[1,2-a]-pyrimidine-3-carboxamide
Authors:István Hermecz  József Engler  Zoltán Mészáros  Gábor Tóth
Affiliation:1. CHINOIN Pharm. and Chem. Works, H-1325 Budapest, P.O. Box 110, Hungary;2. Institute for Drug Research H-1325 Budapest P.O. Box 82, Hungary;3. NMR Laboratory of the Institute for General and Analytical Chemistry, Technical University, H-1111 Budapest, Gellért tér 4. Hungary
Abstract:The title compound /3/ may be transformed into the 3-/methylaminomethylene/--2,3,6,7,8,9-hexahydro-4H-pyrido[1,2-a]pyrimidine-2,4-dione /5E, 5Z/ which is in equilibrium with the 1,2,3,6,7,8-hexahydro tautomer /8E, 8Z/ in DMSO-d6.
Keywords:
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