The stereospecific synthesis of spectinomycin |
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Authors: | D.R White R.D Birkenmeyer R.C Thomas S.A Mizsak V.H Wiley |
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Affiliation: | The Upjohn Company, Kalamazoo, Michigan 49001 USA |
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Abstract: | The first synthesis of spectinomycin, a complex and sensitive antibiotic, is described. The synthesis, which requires only four steps from known materials, has flexibility for modifying either half of the molecule. |
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