二氯菊酸类杀虫剂光学纯度分析方法的研究

报道了旋光性的顺式－2，2－二甲基－3－（2，2－二氯乙烯基）环丙烷羧酸（谷称顺式二氯菊酸）类杀虫剂光学纯度的色谱分析方法。光学活性杀虫剂的顺式－2，2－二甲基－3－（2，2－二氯乙烯基）环丙烷羧酸先与氯化亚砜生成酰氯，一财与S（－）－a-甲基苄胺作用，生成顺式－2，2－二氯－3－异丁烯基环丙烷羧酸非对映异构体的酰胺，经薄层色谱纯，用高效液相色谱进行分析，即可确定中间体的光学纯度。光学纯度一定的中间体经合成至最终产物，其光学纯度保持不变。

Study on Chromatographic Analysis of Optical Purity of Dichloro-Chrysanthemic Acid as a Pesticide

A chromatographic method for determining optical purity of pesticide dichloro chrysanthemic acid was reported. The optical pesticide of cis 2,2 dimethyl 3 (2,2 dichlorovinyi) cyclopropanecarboxylic acid reacted with S( ) a phenylethylamine to produce their alaninates. The products of alaninates were analyzed by HPLC after purified by TLC. In the process of optical cis 2,2 dimethyl 3 (2,2 dichloro vinyi)cyclopropane carboxylic acid changing into optical dichloro chrysanthethemic carboxylate, the optical purity was not changed. Based on these, the optical purity of dichloro chrysanthemic acid could be determined.