Synthesis and properties of polymeric and organo-inorganic amphiphilic sorbents molecularly imprinted with cholesterol |
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| Authors: | I V Polyakova A A Osipenko L N Borovikova N M Ezhova O A Pisarev E N Vlasova B Z Volchek |
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| Institution: | 1.Institute of Macromolecular Compounds,Russian Academy of Sciences,St. Petersburg,Russia;2.Department of Medical Physics,Peter the Great St. Petersburg Polytechnic University,St. Petersburg,Russia |
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| Abstract: | Polymeric and organo-inorganic sorbents molecularly imprinted with cholesterol were synthesized to create selective hemosorbents for efferent therapy of hypercholesterlemia. These sorbents are block copolymers of 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate and granulated organo-inorganic sorbents in which the imprinting was performed in the layer of the above copolymer on the surface of selenium (Se) nanoparticles stabilized with polyvinyl pyrrolidone. The physicochemical and sorption properties of the sorbents were studied. |
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